Magnesium plays a significant role in Phase 2 Liver Detox
Phase 2 Liver Detox is the process in which bind up and pee/poo out excess hormones.
It's hugely important in maintaining hormone balance - especially estrogen balance.
Expert Insight: "Phase II detoxification in the liver is essential for estrogen balance. Without efficient conjugation and excretion of estrogen metabolites, the risk of estrogen dominance and related health issues increases." – Dr. Ann Louise Gittleman, PhD, CNS
Magnesium is a cofactor to many of the enzymatic processes in phase 2 liver detox (it helps the reactions take place) including:
- Conjugation - where we 'bind up' used hormones and toxins with various acids to then excrete them.
- Methylation - where we add a methyl group to these chemicals to enhance their solubility.
- Glutathione synthesis - where we create glutathione, a powerful antioxidant that binds to hormones to excrete them from the body.
Supporting Evidence and Expert Opinions
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Study on Magnesium and Liver Detoxification:
- Title: "Magnesium Deficiency and Impaired Liver Function"
- Authors: Nielsen FH.
- Journal: Nutrition Reviews.
- Year: 2010
- Summary: This study discusses how magnesium deficiency can impair liver function, including detoxification processes. It highlights the importance of adequate magnesium levels for optimal enzymatic activity in the liver.
- Quote: "Magnesium deficiency can lead to impaired liver detoxification, including Phase II conjugation reactions, thereby affecting the metabolism and excretion of hormones like estrogen."
Expert Insight:"Magnesium is a critical cofactor for numerous enzymes involved in Phase II liver detoxification. Its role in processes like sulfation, glucuronidation, and methylation underscores its importance in maintaining hormonal balance and preventing estrogen dominance." – Dr. Joseph Pizzorno, ND
Expert Insight:"Supporting liver detoxification pathways with essential nutrients like magnesium is vital for hormone balance. Magnesium's involvement in key enzymatic reactions ensures efficient detoxification and excretion of estrogen metabolites." – Dr. Mark Hyman, MD
Overall, Magnesium plays a significant role in hormone balance by aiding Phase 2 Liver Detox. Without it, your body lacks the tools to power these various enzymatic reactions, and so you will not be able to flush out used hormones.
But that's not all that Magnesium is good for. Its other key benefits are for reducing blood pressure, balancing blood sugar levels, and helping you sleep.
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